Publication - Abstract
May 13, 2021
Nature Communications
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Publication - Abstract
May 13, 2021
Nature Communications
Publication - Abstract
Apr 20, 2021
ACS Biomaterials Science & Engineering
Publication - Abstract
Apr 13, 2021
Pharmaceutics
Publication - Abstract
Apr 08, 2021
Nanomaterials
Publication - Abstract
Mar 23, 2021
ACS Nano
Publication - Abstract
Mar 18, 2021
European Journal of Pharmaceutics and Biopharmaceutics
Use of the frit-inlet channel improves MD-AF4 analysis of LNP-RNA.
A robust method for AF4 separation of LNP-RNA has been developed and tested on two different platform.
The method meets all the ISO stan...
Publication - Abstract
Mar 18, 2021
Molecular Therapy
Publication - Abstract
Mar 16, 2021
ACS Nano
Publication - Abstract
Mar 13, 2021
Molecular Therapy Nucleic Acids
Publication - Abstract
Mar 12, 2021
Pharmaceutics
Publication - Abstract
Feb 16, 2021
Advanced Materials
Publication - Abstract
Feb 16, 2021
Communications Biology
Publication - Abstract
Feb 11, 2021
Nano Letters
Publication - Abstract
Jan 28, 2021
Hepatology
Publication - Abstract
Jan 08, 2021
Scientific Reports
Publication - Abstract
Dec 10, 2020
Journal of Orthopaedic Research
Publication - Abstract
Nov 30, 2020
International Journal of Pharmaceutics
Publication - Abstract
Nov 26, 2020
European Journal of Pharmaceutics and Biopharmaceutics
Publication - Abstract
Nov 18, 2020
Science Advances
Publication - Abstract
Nov 15, 2020
pharmaceutics
Publication - Abstract
Oct 29, 2020
Journal of Medicinal Chemistry
Publication - Abstract
Oct 17, 2020
Journal of Controlled Release
Publication - Abstract
Oct 06, 2020
ACS Applied Nano Materials
Publication - Abstract
Sep 25, 2020
ACS Applied Nano Materials
Publication - Abstract
Sep 10, 2020
Drug Delivery Letters
Publication - Abstract
Sep 01, 2020
International Journal of Pharmaceutics
Publication - Abstract
Aug 25, 2020
ACS Applied Nano Materials
Publication - Abstract
Aug 18, 2020
Nucleic Acids Research
In this paper Alnylam Pharmaceuticals, developer of RNAi therapeutics ONPATTRO® and GIVLAARI®, investigates the biological origins of the extended duration of N-acetylgalactosamine silencing RNA (GalNAc-siRNA) activity observed in vivo.
Publication - Abstract
Jul 19, 2020
Current Topics in Microbiology and Immunology
Publication - Abstract
Jul 03, 2020
Journal of Medical Virology
Publication - Abstract
Jul 01, 2020
Journal of Controlled Release
Publication - Abstract
Jun 23, 2020
Advanced Functional Materials
Publication - Abstract
Jun 22, 2020
Small
Publication - Abstract
Jun 15, 2020
Chemical Engineering Journal
Publication - Abstract
Jun 15, 2020
Journal of Colloid and Interface Science
Publication - Abstract
Jun 11, 2020
Pharmaceuticals
Publication - Abstract
Jun 04, 2020
Nano Letters
Publication - Abstract
May 26, 2020
Cellular and Molecular Bioengineering
Lipid based nanoparticles (LNPs) are clinically successful vectors for hepatic delivery of nucleic acids. These systems are being developed for non-hepatic delivery of mRNA for the treatment of diseases like cystic fibrosis or retinal degeneration as well as infectious disease...
Publication - Abstract
May 06, 2020
Nano Letters
Publication - Abstract
Apr 24, 2020
Cells
Publication - Abstract
Apr 08, 2020
Molecular Pharmaceutics
Publication - Abstract
Apr 06, 2020
ACS Nano
Publication - Abstract
Mar 27, 2020
Scientific Reports
Publication - Abstract
Feb 29, 2020
Biomaterials
Publication - Abstract
Feb 26, 2020
International Journal of Molecular Sciences
Publication - Abstract
Feb 24, 2020
Pharmaceutical Research
Publication - Abstract
Feb 10, 2020
Drug Delivery and Translational Research
Publication - Abstract
Nov 28, 2019
Journal of Controlled Release
Publication - Abstract
Nov 08, 2019
Pharmaceutics
Publication - Abstract
Oct 24, 2019
Circulation Research
Publication - Abstract
Sep 01, 2019
Journal of Colloid and Interface Science
Publication - Abstract
Aug 22, 2019
Drug Delivery Systems
Publication - Abstract
Jun 19, 2019
Dalton Transactions
Publication - Abstract
Jun 17, 2019
Lab on a Chip
Publication - Abstract
May 17, 2019
Methods in Molecular Biology, vol 1974
Publication - Abstract
Feb 15, 2019
International Journal of Nanomedicine
Publication - Abstract
Jan 29, 2019
Pharmaceutics
Publication - Abstract
Dec 09, 2018
Pharmaceutics
Publication - Abstract
Nov 30, 2018
Nanoscale Advances
Publication - Abstract
Nov 29, 2018
International Journal of Pharmaceutics
Publication - Abstract
Nov 12, 2018
Biomaterials Science
Publication - Abstract
Sep 17, 2018
Bioengineering and Translational Medicine
Publication - Abstract
Apr 18, 2018
Journal of Leukocyte Biology
Mast cells are important immune cells that have significant roles in mediating allergy and asthma. Therefore, studying the molecular mechanisms regulating these and other processes in mast cells is important to elucidate. Methods such as lipofectio...
Publication - Abstract
Apr 05, 2018
Advanced Drug Delivery Reviews
Nanopharmaceuticals aim at translating the unique features of nano-scale materials into therapeutic products and consequently their development relies critically on the progression in manufacturing technology to allow scalable processes complying w...
Publication - Abstract
Mar 14, 2018
Molecular Therapy
Publication - Abstract
Mar 07, 2018
Advanced Material
The advancement of nanotechnology toward more sophisticated bioinspired approaches has highlighted the gap between the advantages of biomimetic and biohybrid platforms and the availability of manufacturing processes to scale up their production. Th...
Publication - Abstract
Feb 12, 2018
Journal of Nanobiotechnology
The process of optimization and fabrication of nanoparticle synthesis for preclinical studies can be challenging and time consuming. Traditional small scale laboratory synthesis techniques suffer from batch to batch variability. Additionally, the p...
Publication - Abstract
Jan 29, 2018
Nature Nanotechnology
Previous studies have identified relevant genes and signalling pathways that are hampered in human disorders as potential candidates for therapeutics. Developing nucleic acid-based tools to manipulate gene expression, such as short interfering RNAs...
Publication - Summary
Sep 01, 2017
Scientific Reports
Currently, clinically approved medicines with liposomal formulations have a combined annual revenue of approximately $100 million USD, but their difficult and expensive production methods make more widespread use prohibitive. Microfluidic devi...
Publication - Abstract
May 27, 2017
Journal of Pharmaceutical Sciences
Lipid-polymer hybrid nanoparticles (NPs) are advantageous for drug delivery. However, their intracellular trafficking mechanism and relevance for oral drug absorption are poorly understood. In this study, self-assembled core-shell lipid-polymer hyb...
Publication - Abstract
Jan 10, 2017
International Journal of Pharmaceutics
Publication - Abstract
Nov 21, 2016
Nanoscale
Publication - Abstract
Nov 10, 2016
International Journal of Pharmaceutics
Liposomes have been the centre of attention in research due to their potential to act as drug delivery systems. Although its versatility and manufacturing processes are still not scalable and reproducible.
Publication - Abstract
Jul 13, 2015
Journal of the American Chemical Society
Publication - Abstract
May 15, 2015
International Journal of Pharmaceutics
Besides their well-described use as delivery systems for water-soluble drugs, liposomes have the ability to act as a solubilizing agent for drugs with low aqueous solubility. However, a key limitation in exploiting liposome technology is ...