CREATE
TRANSFORMATIVE
MEDICINES
TRANSFORMATIVE
MEDICINES
A global leader in innovative solutions for the discovery, development, and manufacture of novel nanoparticle medicines.
Every Stage
of Development
of Development
No two journeys are the same.
Finding trusted partners in the journey from discovery to clinical manufacturing becomes as critical as the journey itself. PNI is uniquely positioned to offer the flexibility needed to move products from the clinical development stages through to commercial scale in a nimble and agile manner, accelerating the research and drug development process.
We provide a breadth of expertise in formulation and clinical solutions, a proprietary platform and reagents. We empower life science researchers and drug developers to create transformative medicines that significantly improve human well being.
Thousands of compounds may be potential candidates for development as a medical treatment. Rapidly prepare low-volume nanoparticle formulations with the push of a button on the Spark™ or learn how Formulation Solutions can help with proof-of-concept nanoparticle formulations. Nanomedicine is playing a key role in pharmaceutical discovery, largely in the form of nanoparticle-based delivery systems for drugs.
After early testing, only a small number of compounds look promising and call for further study. In this stage, optimizing a wide range of nanomedicine formulations with the NanoAssemblr® Benchtop or
the Blaze™
depending on your volumes to allow you to gather the data on the effectiveness, required dosing and safety of a new therapy.
Develop nanoparticle drugs for clinical evaluation and to support clinical development for their commercialization. Scalable manufacturing is a significant challenge to making revolutionary medicine and Formulation Solutions is ready to assist you in your nanoparticle manufacturing process development. PNI provides a custom Clinical Solution for development and commercial supply.
Get Started
To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.
Technology
Our technology provides a seamless path forward to larger experimental studies, all the way to the clinic: low volume prototype formulations are easily scaled-up using larger instruments of the NanoAssemblr® family, which provides microfluidic mixing and manufacturing of nanoparticles.
Areas of Interest
Nanomedicines span many areas of interest. Explore resources like papers, application notes, scientific posters, webinars and more to see how nanotechnology is transforming
medicine.
over
70%
of top pharmaceutical companies work with PNI
200+
instruments are installed
worldwide
80+
biopharmaceutical labs use NanoAssemblr® instruments for nanomedicine
drug development
Innovations that accelerate the drug development journey and enable the production of more sophisticated and powerful nanomedicines is our passion. We don’t do it alone, we pursue strategic collaborations that enable researchers to move quickly
in the drug development process. Contact our Business Development Team.
PNI Feature in BioWorld
"As we bite off different problems and succeed on those, we can leverage those technologies," CEO Taylor explains. "We like to think that we're democratizing and lowering the barrier for people to get into these important technologies."
Evonik Collaboration
PNI announces a manufacturing collaboration agreement with Evonik for the tech transfer of the NanoAssemblr® system to Evonik Canada for late-stage clinical research.
License Agreement with Entos Pharmaceuticals
Precision NanoSystems and Entos Pharmaceuticals sign license agreement for the use of the NanoAssemblr® platform for scale-up and GMP manufacturing of nanomedicines.
Resource Center
Poster
July 01, 2018
Application Note
July 01, 2018
Publication - Abstract
April 26, 2018
Small Methods
State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery
Read MorePublication - Abstract
February 27, 2018
Cell Reports
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Read MorePublication - Abstract
November 01, 2018
Neuron
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
Read MorePublication - Abstract
October 29, 2018
Nature Communications
Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes
Read MoreStay Informed
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