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CREATE
TRANSFORMATIVE
MEDICINES
A global leader in innovative solutions for the discovery, development, and manufacture of novel nanoparticle medicines.
 
Every Stage
of Development

No two journeys are the same.

 

Finding trusted partners in the journey from discovery to clinical manufacturing becomes as critical as the journey itself.

 

PNI is uniquely positioned to offer the flexibility needed to move products from the clinical development stages through to commercial scale in a nimble and agile manner, accelerating the research and drug development process.

 

We provide a breadth of expertise in formulation and clinical solutions, a proprietary platform and reagents. We empower life science researchers and drug developers to create transformative medicines that significantly improve human well being.

 

Formulation Solutions Formulation Solutions Formulation Solutions
Thousands of compounds may be potential candidates for development as a medical treatment. Rapidly prepare low-volume nanoparticle formulations with the push of a button on the Spark™ or learn how Formulations Solutions can help with proof-of-concept nanoparticle formulations. Nanomedicine is playing a key role in pharmaceutical discovery, largely in the form of nanoparticle-based delivery systems for drugs. 
After early testing only a small number of compounds look promising and call for further study. In this stage, optimizing a wide range of nanomedicine formulations with the NanoAssemblr™ Benchtop or the Blaze™ depending on your volumes to allow you to gather the data on the effectiveness, required dosing and safety of a new therapy. 
Develop nanoparticle drugs for clinical evaluation and to support clinical development for their commercialization. Scalable manufacturing is a significant challenge to making revolutionary medicine and Formulations Solutions is ready to assist you in your nanoparticle manufacturing process development. PNI provides a custom Clinical Solution for development and commercial supply.

Get Started

To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

Get in Touch
Technology

Our technology provides a seamless path forward to larger experimental studies, all the way to the clinic: low volume prototype formulations are easily scaled-up using larger instruments of the NanoAssemblr™ family, which provides microfluidic mixing and manufacturing of nanoparticles.

 


Mixtures
Phases
Benchtop
The NanoAssemblr™ Benchtop
Areas of Interest
Nanomedicines span many areas of interest. Explore resources like papers, application notes, scientific posters, webinars and more to see how nanotechnology is transforming medicine. 
Particles
over
70%
of top pharmaceutical companies work with PNI
200+
instruments are installed worldwide
80+
biopharmaceutical labs use NanoAssemblr™ instruments for nanomedicine drug development
Innovations that accelerate the drug development journey and enable the production of more sophisticated and powerful nanomedicines is our passion. We don’t do it alone, we pursue strategic collaborations that enable researchers to move quickly in the drug development process. Contact our Business Development Team

 

 

 

 

 

NYC Nanomedicine Symposium—July 21, 2018

 

Join us to explore challenges and solutions in drug development and hear from industry leaders on medicine’s personalized future.

Evonik Collaboration

 

PNI announces a manufacturing collaboration agreement with Evonik for the tech transfer of the NanoAssemblr system to Evonik Canada for late-stage clinical research.

Record Growth in 2017

 

19 of the top 25 pharmaceutical companies use the NanoAssemblr™ platform and PNI’s technology was featured in 100+ peer-reviewed publications.

 

Upcoming Events See All

July
21 - 22
2018

PNI 2018 Nanomedicine Symposium: Shaping the Future

Past Symposiums have included distinguished researchers from around the world who are transforming nanomedicine technologies.

July
22 - 25
2018

CRS - Controlled Release Society Annual Meeting and Exposition

In CRS 2018, members create the future of delivery science and technology through fundamental delivery research, development,



Visit Event Website

September
02 - 06
2018

CLINAM - European and Global Summit for Clinical Nanomedicine, Targeted Delivery and Precision Medicine

The goal of the CLINAM Foundation is to contribute to the benefit of patients and society by exploring and translating leadin



Visit Event Website

Resource Center

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

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Application Note

July 01, 2018

Seamless scale up of liposomal verteporfin formulations using the NanoAssemblr™ Platform

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Publication - Abstract

April 26, 2018

Small Methods

State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P., & Schiffelers, R. M.

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Publication - Abstract

February 27, 2018

Cell Reports

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

J. Finn, A. Smith, M. Patel, L. Shaw, M. Youniss, J. Heteren, T. Dirstine, C. Ciullo, R. Lescarbeau, J. Seitzer, R. Shah...

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Publication - Abstract

July 04, 2018

Nature communications

Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

M Yu, L Xu, F Tian, Q Su, N Zheng, Y Yang

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Publication - Abstract

June 15, 2018

Molecular therapy

Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis

E Robinson, KD MacDonald, K Slaughter, M McKinney

Read More
Resource Center

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