A global leader in innovative solutions for the discovery, development, and manufacture of novel nanoparticle medicines.



Every Stage
of Development

No two journeys are the same.


Finding trusted partners in the journey from discovery to clinical manufacturing becomes as critical as the journey itself. PNI is uniquely positioned to offer the flexibility needed to move products from the clinical development stages through to commercial scale in a nimble and agile manner, accelerating the research and drug development process.


We provide a breadth of expertise in formulation and clinical solutions, a  proprietary platform and reagents. We empower life science researchers and drug developers to create transformative medicines that significantly improve human well being.



Formulation Solutions Formulation Solutions Formulation Solutions
Thousands of compounds may be potential candidates for development as a medical treatment. Rapidly prepare low-volume nanoparticle formulations with the push of a button on the Spark™ or learn how Formulation Solutions can help with proof-of-concept nanoparticle formulations. Nanomedicine is playing a key role in pharmaceutical discovery, largely in the form of nanoparticle-based delivery systems for drugs.
After early testing, only a small number of compounds look promising and call for further study. In this stage, optimizing a wide range of nanomedicine formulations with the NanoAssemblr® Benchtop or the Blaze  depending on your volumes to allow you to gather the data on the effectiveness, required dosing and safety of a new therapy.
Develop nanoparticle drugs for clinical evaluation and to support clinical development for their commercialization. Scalable manufacturing is a significant challenge to making revolutionary medicine and Formulation Solutions is ready to assist you in your nanoparticle manufacturing process development. PNI provides a custom Clinical Solution for development and commercial supply.
Partners and Collaborators


  • "As an Evonik affiliate specialized in liposomal drug delivery systems, we are pleased to offer our clients access to the NanoAssemblr GMP System, which will aid in the translation of drug candidates to clinical testing and ideally to commercial use." 
    - Don Enns, Vice President of Evonik Vancouver Laboratories
  • "We are excited about this promising collaboration and hope that it will propel our work forward as the ncRNA Core Facility focuses on the non-coding RNA portions of the genome for [the] discovery of novel biomarkers and targets for therapeutics from human disease tissue and clinical trial specimens."
    - Frank Slack, Director of the Harvard Medical School Initiative for RNA Medicine (HIRM) at BIDMC
  • "Ajinomoto Bio-Pharma Services has audited the PNI facilities in Vancouver and has qualified PNI's NanoAssemblr® GMP System and its components. We are excited to work with PNI to offer their purpose-designed manufacturing technology and unique nanomedicine expertise to our clients for the manufacture of nanoparticle-based medicines" 
    - Kristin DeFife, Ph.D., Vice President and Head of US Operations of Ajinomoto Bio-Pharma Services

Get Started

To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

Get in Touch

Our technology provides a seamless path forward to larger experimental studies, all the way to the clinic: low volume prototype formulations are easily scaled-up using larger instruments of the NanoAssemblr® family, which provides microfluidic mixing and manufacturing of nanoparticles.


Areas of Interest
Nanomedicines span many areas of interest. Explore resources like papers, application notes, scientific posters, webinars and more to see how nanotechnology is transforming medicine. 
of top pharmaceutical companies work with PNI

instruments are installed


biopharmaceutical labs use NanoAssemblr® instruments for nanomedicine drug development
Innovations that accelerate the drug development journey and enable the production of more sophisticated and powerful nanomedicines is our passion. We don’t do it alone, we pursue strategic collaborations that enable researchers to move quickly in the drug development process. Contact our Business Development Team.






PNI Feature in BioWorld


"As we bite off different problems and succeed on those, we can leverage those technologies," CEO Taylor explains. "We like to think that we're democratizing and lowering the barrier for people to get into these important technologies."

Evonik Collaboration


PNI announces a manufacturing collaboration agreement with Evonik for the tech transfer of the NanoAssemblr® system to Evonik Canada for late-stage clinical research.

License Agreement with Entos Pharmaceuticals


Precision NanoSystems and Entos Pharmaceuticals sign license agreement for the use of the NanoAssemblr® platform for scale-up and GMP manufacturing of nanomedicines.


Upcoming Events See All

Resource Center

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

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Publication - Abstract

November 29, 2018

International Journal of Pharmaceutics

Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-lin...

N. Forbes, MT. Hussain, ML. Briuglia, DY. Edwards, JH. terHorst, N. Szita, Y. Perrie

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July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

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Publication - Abstract

April 26, 2018

Small Methods

State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P., & Schiffelers, R. M.

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Publication - Abstract

February 27, 2018

Cell Reports

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

J. Finn, A. Smith, M. Patel, L. Shaw, M. Youniss, J. Heteren, T. Dirstine, C. Ciullo, R. Lescarbeau, J. Seitzer, R. Shah...

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Application Note

January 02, 2018

Seamless scale up of siRNA LNP formulations using the NanoAssemblr® platform

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Resource Center

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