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To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.
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Reduce the risk during transition from Research into Development
Reduce cost since downstream equipment is available at CMO facilities
Accelerate timelines to Investigational New Drug Applications
The NanoAssemblr Ignite NxGen Dilution Cartridge enables automated in-line dilution of the nanoparticles as they emerge from the microfluidic mixer.
Intuitive software allows frequently used manufacturing recipes to be stored minimizing batch-to-batch and user variability.
System is ready in 3 simple steps with no priming or cleaning required. Genetic medicine formulations can be prepared in minutes allowing rapid optimization of particle properties.
The Ignite brings the highly scalable power of NxGen microfluidic technology to the bench. The NxGen mixer uses precisely controlled time-invariant mixing to reproducibly generate optimal particles through a single mixer across scales.
Advanced microfluidics in an automated system removes batch-to-batch and user-to-user variability.
Easy setup with touch screen interface, saved recipes and a single-use fluid path that eliminates priming and cleaning enables a streamlined workflow.
Tune particle size with precise control over fluid flow rates.
Formulate small molecules, peptides and, nucleic acids into lipid, polymer or hybrid nanoparticles, and more.
Formulation runs require less than a minute. Over 50 formulations can be completed in a day for rapid optimization.
Easily scale between 1mL and 20mL formulations on the Ignite. Optimized formulations can be predictably scaled to advanced preclinical and clinical scale with Blaze™ and GMP Systems with NxGen technology.
To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.
Get in Touch
1
An aqueous phase and a miscible solvent containing dissolved nanoparticle precursors are injected into each inlet of the NanoAssemblr cartridge2
Under laminar flow, the two phases do not immediately mix3
Microscopic features engineered into the channel reproducibly control the mixing of the two streams4
Rapid, controlled, homogenous mixing produces homogeneous nanoparticles
Ignite Demo with GenVoy Training Kit
Ignite Informational Presentation
GenVoy Ignite Demo
NanoAssemblr Ignite cartridges feature exclusive NxGen microfluidic technology that preserves time-invariant particle formation conditions and allows future scale up through a single mixer from ml/min to L/h.
Ignite cartridges are single use. No priming or cleaning required for an efficient workflow. Ignite cartridges are compatible with a wide range of solvents to make a diverse array of nanomedicine formulations.
Ignite cartridges with NxGen Technology are also available with automated in-line dilution of the nanoparticles to allow modelling of the processes that will be required for future GMP production.
Publication - Abstract
December 16, 2020
pharmaceutics
Publication - Abstract
December 16, 2020
Advanced Therapeutics
Publication - Abstract
November 30, 2020
International Journal of Pharmaceutics
Publication - Abstract
November 19, 2020
Molecular Pharmaceutics
Publication - Abstract
November 18, 2020
Science Advances