Power to Explore


GenVoy-ILM, an off-the-shelf Research Use Only lipid nanoparticle reagent, lowers the barriers to developing genetic medicines

Explore Genetic Medicine with GenVoy-ILM



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The RNA chemistry, the lipid composition and the manufacturing process affect characteristics of the resultant lipid nanoparticle.



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GenVoy-ILM Demonstration on the NanoAssemblr® Ignite

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GenVoy-ILM™ is an ionizable lipid mix that enables the rapid and easy production of RNA-loaded lipid nanoparticles (LNPs) using the NanoAssemblr®Platform.  GenVoy-ILM is the simplest way to get started with LNPs - the most advanced non-viral technology for delivering nucleic acids.



An exclusive ionizable cationic lipid mix for preclinical development


With applications in Genetic Vaccine, Gene Therapy and Cell Therapy


For the treatment of cancer, rare disease, and infectious disease.

LNPs mimic low-density lipoproteins and are taken up through an endogenous pathway where they are designed to trigger the release of nucleic acids in the cytoplasm.


Endogenous Uptake


Deliver mRNA for Gene Expression


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A single injection of GenVoy-ILM Factor VII siRNA-LNP was administered to mice via the tail vein at the RNA doses indicated and plasma levels of Factor VII protein were measured up to 21 days post-administration.

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Lipid Nanoparticles

LNPs contain a pH-sensitive ionizable cationic lipid that attract anionic nucleic acids to form the core of self-assembling nanoparticle to ensure high encapsulation.


At physiological pH, LNPs are neutral, eliminating a mechanism of toxicity seen with permanently cationic molecules.


These same pH-sensitive lipids are responsible for responding to the acidic environment of the endosome and triggering the disruption of the endosome and release of the nucleic acid into the cell.



Learn More About Lipid Nanoparticles

Nucleic Acid Lipid Nanoparticle


Both The Chemistry And The Process Determine The Outcome


LNPs made with the NanoAssemblr®Platform have a unique homogeneous structure that is more effective compared to other methods of manufacture such as T-tube mixing. 

Use Genvoy-ILM for: 


Gene silencing Gene editing 
Gene expression Gene modulation 

Use GenVoy-ILM to encapsulate and deliver: 


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Product Information

GenVoy-ILM is a pre-blended lipid mix in ethanol and is available in two formats with or without added dye for visualization.


2 mL, 5 mL

GenVoy-ILM Vials

The Chemistry And The Process Affect The Outcome 

LNPs made with the NanoAssemblr platform exhibit a unique homogeneous core structure with exceptionally consistent size within and between batches, which has been shown to be more potent than particles made by other methods. 



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To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

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Resource Center


April 26, 2016

Application of Microfluidic Mixing for Generating Limit Size Nanoparticles

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Publication - Abstract

November 21, 2016


Cationic Switchable Lipids: pH-triggered Molecular Switch for siRNA Delivery

W. Viricel, S. Poirier, A. Mbarek, R.M. Derbali, G. Mayer and J. Leblond

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February 09, 2022

A Novel RNA Lipid Nanoparticle Platform: Gene-editing CAR T Cells for Off-the-Shelf Cancer Therapy

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August 10, 2016

NanoAssemblr® Benchtop | Dr. Gesine Heuck, PNI Tech Talk

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August 04, 2017

Ocular Delivery of mRNA - Patrick Baumhof, CureVac AG

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July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

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