Power to Explore


GenVoy-ILM, an off-the-shelf Research Use Only lipid nanoparticle reagent, lowers the barriers to developing genetic medicines

Explore Genetic Medicine with GenVoy-ILM



Screen Shot 2020-04-29 at 12.22.09 AM

The RNA chemistry, the lipid composition and the manufacturing process affect characteristics of the resultant lipid nanoparticle.



Download the Brochure

GenVoy-ILM Demonstration on the NanoAssemblr® Ignite

Screen Shot 2020-04-29 at 12.11.19 AM

GenVoy-ILM™ is an ionizable lipid mix that enables the rapid and easy production of RNA-loaded lipid nanoparticles (LNPs) using the NanoAssemblr®Platform.  GenVoy-ILM is the simplest way to get started with LNPs - the most advanced non-viral technology for delivering nucleic acids.



An exclusive ionizable cationic lipid mix for preclinical development


With applications in Genetic Vaccine, Gene Therapy and Cell Therapy


For the treatment of cancer, rare disease, and infectious disease.

LNPs mimic low-density lipoproteins and are taken up through an endogenous pathway where they are designed to trigger the release of nucleic acids in the cytoplasm.


Endogenous Uptake


Deliver mRNA for Gene Expression


Screen Shot 2019-06-21 at 2.58.04 PM

A single injection of GenVoy-ILM Factor VII siRNA-LNP was administered to mice via the tail vein at the RNA doses indicated and plasma levels of Factor VII protein were measured up to 21 days post-administration.

Screen Shot 2020-04-29 at 12.39.25 AM
Screen Shot 2020-04-29 at 12.39.40 AM
Screen Shot 2020-04-29 at 12.40.06 AM
Lipid Nanoparticles

LNPs contain a pH-sensitive ionizable cationic lipid that attract anionic nucleic acids to form the core of self-assembling nanoparticle to ensure high encapsulation.


At physiological pH, LNPs are neutral, eliminating a mechanism of toxicity seen with permanently cationic molecules.


These same pH-sensitive lipids are responsible for responding to the acidic environment of the endosome and triggering the disruption of the endosome and release of the nucleic acid into the cell.



Learn More About Lipid Nanoparticles

Nucleic Acid Lipid Nanoparticle


Both The Chemistry And The Process Determine The Outcome


LNPs made with the NanoAssemblr®Platform have a unique homogeneous structure that is more effective compared to other methods of manufacture such as T-tube mixing. 

Use Genvoy-ILM for: 


Gene silencing Gene editing 
Gene expression Gene modulation 

Use GenVoy-ILM to encapsulate and deliver: 


Screen Shot 2020-04-29 at 12.11.38 AM
Screen Shot 2020-04-29 at 12.12.10 AM

Product Information

GenVoy-ILM is a pre-blended lipid mix in ethanol and is available in two formats with or without added dye for visualization.


2 mL, 5 mL

GenVoy-ILM Vials

The Chemistry And The Process Affect The Outcome 

LNPs made with the NanoAssemblr platform exhibit a unique homogeneous core structure with exceptionally consistent size within and between batches, which has been shown to be more potent than particles made by other methods. 



Get Started

To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

Get in Touch

Resource Center

Publication - Abstract

February 29, 2020


Nose-to-brain Delivery of Enveloped RNA - Cell Permeating Peptide Nanocomplexes for the Treatment of Neurodege...

E. Samaridou, H. Walgrave, E. Salta, D.M. Álvarez, V. Castro-López, M. Loza, and M.J. Alon...

Read More 阅读更多

Application Note

March 15, 2022

Genome Editing of Human Primary T Cells with Lipid Nanoparticles

Read More 阅读更多 PDF


July 26, 2016

Microfluidics in Manufacturing of mRNA Nanomedicines | Heinrich Haas, BioNTech

Read More 阅读更多

Publication - Summary

February 07, 2019

Molecular Therapy Nucleic Acids

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

K.J Hassett, K.E. Benenato, E. Jacquinet, L.A. Brito, et al.

Read More 阅读更多


September 14, 2018

From Concept to Reality: Development of Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics - Marti...

Read More 阅读更多


July 21, 2022

Translating mRNA-based Medicines from Concept to Clinic

Read More 阅读更多
Resource Center 资源中心
Sign Up and Stay Informed
Sign up today to automatically receive new Cytiva, formerly Precision NanoSystems application notes, conference posters, relevant science publications, and webinar invites.