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The
NanoAssemblr®
Benchtop
The NanoAssemblr® Benchtop has been discontinued. To advance transformative medicines, please see our NanoAssemblr® Ignite™.
Overcome key challenges
in nanomedicine development
with the Benchtop.
outstanding reproducibility
Computer control removes batch-to-batch and user variability.
intuitive workflow
Advanced microfluidics is simplified with easy connections and visual software.
controlled assembly
Tune particle size with precise control over fluid flow rates.
versatile
Formulate small molecules, peptides and, nucleic acids into lipid, polymer or hybrid nanoparticles, and more.
speedy and efficient
Formulation runs require less than a minute. 30 - 40 formulations can be completed in a day for rapid optimization.
scalable
Easily scale between 1mL and 15mL formulations on the Benchtop. Optimized formulations can be transferred to advanced preclinical and clinical scale with the Blaze™ and GMP Systems.
Easily optimize
nanoparticle size
Use simple software parameters such as Total Flow Rate (TFR) and Flow Rate Ratio (FRR) to fine tune particle size.
Optimize liposomal drug delivery systems
Develop polymeric drug delivery systems
Robust,
reproducible
process
Minimizing process variability isolates the effects of materials, solvent choice, and concentrations on desired outcomes, enabling rational formulation design.
Batch-to-Batch Reproducibility from Independent Users
Isolate Effects of Formulation Parameters
Advanced Technology for
Advanced Nanomedicines
Advanced Nanomedicines
Non-turbulent microfluidic mixing provides unparalleled control over nanoparticle assembly that is scalable from discovery to the clinic.
1
An aqueous phase and a miscible solvent containing dissolved nanoparticle precursors are injected into each inlet of the NanoAssemblr cartridge2
Under laminar flow, the two phases do not immediately mix3
Microscopic features engineered into the channel reproducibly control the mixing of the two streams4
Rapid, controlled, homogenous mixing produces homogeneous nanoparticles
Videos
Overview
NanoAssemblr Technology
Benchtop Demo
Benchtop Cartridges
NanoAssemblr® Benchtop cartridges are semi-disposable and compatible with a wide range of solvents to make a diverse array of nanomedicine formulations.
The NanoAssemblr® Benchtop system is designed for rapid prototyping of novel nanoparticle formulations of 1 to 15mL, that would be difficult to make with alternative manufacturing methods. The software enables the control of input mixing parameters for optimizing particle characteristics such as size and encapsulation efficiency.Download Brochure
Resource Center
Publication - Abstract
September 15, 2021
Vaccine
Publication - Abstract
August 19, 2021
Publication - Abstract
August 11, 2021
Advanced Science
Publication - Abstract
May 13, 2021
Nature Communications
Publication - Abstract
April 20, 2021
ACS Biomaterials Science & Engineering