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NanoAssemblr™
Product Suite
Comparison
Precision NanoSystems’ proprietary NanoAssemblr™ Platform enables the rapid and controlled manufacture of nanomedicines.
product-comparison-header

Discovery

The
NanoAssemblr™
Spark
Freedom to Discover
With Instant Microliter
Nanomedicine Formulations

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nanoassemblr-spark
sample-recovery
Unmatched
Sample Recovery

Advanced microfluidics allow microliter formulation volumes with near complete sample recovery.

intuitive-operation
Intuitive Operation

Simply pipette starting materials into wells, push a button, and pipette completed formulations out.

rapid-production

Rapid Production

The Spark formulation process requres less than 5 seconds, allowing hundreds of formulations to be made in hours.

robust-process

Robust Process

Electronic control minimizes batch-to-batch and user variability.

workflow-integration
Workflow Integration

The Spark system is designed for operation in a sterile biosafety hood, so formulations can be made on-demand, and appled to cells in culture.

scalable

Scalable

Shared microfluidic mixing technology allow formulations to be scaled across the NanoAssemblr Platform to accellerate future development.

Preclinical

The
NanoAssemblr™
Benchtop
Develop Future Nanomedicines

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benchtop
outstanding-reproducibility
Outstanding
Reproducibility

Computer control removes batch-to-batch and user variability

intuitive-operation

Intuitive work flow

Advanced microfluidics are simplified with easy connections, and visual software

controlled-assembly

Controlled Assembly

Tune particle size with precise control over fluid flow rates

versatile

Versatile

Formulate small molecules, peptides and nucleic acids into lipid, polymer or hybrid nanoparticles, and more.

speedy

Speedy and Efficient

Formulation runs require less than a minute. 30 - 40 formulations can be completed in a day for rapid optimization

scalable

Scalable

Easily scale between 1mL and 15mL formulations on the Benchtop. Optimized formulations can be transfered to advanced preclinical and clinical scale with the Blaze™ and 8x Scale-up systems

The
NanoAssemblr™
Blaze
Advance Preclinical
Nanomedicine Programs


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blaze

speedy

Speedy and Efficient

Formulation runs require less than a minute. 30 - 40 formulations can be completed in a day for rapid optimization

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Easy Scaleup

Easy Scaleup of Formulations developed on the NanoAssemblr Benchtop

rapid-production

High capacity

Greater formulation capacity with the simplicity and efficiency of the NanoAssemblr Benchtop

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Validation
of inline dilution

Validation of Inline Dilution up to 5L

controlled-assembly

high range
of formulation

Formulation of 10 mL to 1L batches

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Scalable upstream
and downstream

Scale-up development of upstream and downstream processes

Manufacturing

Scale-up Program
Continuous flow microfluidic platform designed for scale-up manufacturing of nanoparticles under cGMP conditions. The Scale-up system’s formulation results are in sync with NanoAssemblr Benchtop and Blaze-generated particles.

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Scale-Up System
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What is Nanomedicine?
Nanomedicines represent the next paradigm in drug innovation, and current research has demonstrated improved efficacy, reduced side effects and revolutionary new treatment modalities like gene therapy and targeted medicine
Our technology is only the beginning
The NanoAssemblr™ Platform is a unique product offering that uses proprietary microfluidic mixers optimized for the manufacture of nanomedicines.

Get Started

To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

Get in Touch

Resource Center

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

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Application Note

July 01, 2018

Seamless scale up of liposomal verteporfin formulations using the NanoAssemblr™ Platform

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Publication - Abstract

April 26, 2018

Small Methods

State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P., & Schiffelers, R. M.

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Publication - Abstract

February 27, 2018

Cell Reports

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

J. Finn, A. Smith, M. Patel, L. Shaw, M. Youniss, J. Heteren, T. Dirstine, C. Ciullo, R. Lescarbeau, J. Seitzer, R. Shah...

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Poster

August 04, 2018

Microfluidic Manufacture of PLGA Nano and Microparticle Drug Delivery Vehicles

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Poster

August 01, 2018

Microfluidics-based Manufacture of PEG-b-PLGA Block Copolymer Nanoparticles for the Delivery of Small Molecule Therapeutics

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Resource Center