Publication - Abstract
Oct 01, 2021
Biomaterials
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Publication - Abstract
Oct 01, 2021
Biomaterials
Publication - Abstract
Apr 08, 2021
Nanomaterials
Publication - Abstract
Mar 15, 2021
Acta Biomaterilia
Publication - Abstract
Dec 21, 2020
Molecular Therapy
Publication - Abstract
Dec 10, 2020
Journal of Orthopaedic Research
Publication - Abstract
Dec 07, 2020
Journal of Controlled Release
Publication - Abstract
Nov 02, 2020
Journal of Controlled Release
Publication - Abstract
Oct 06, 2020
ACS Applied Nano Materials
Publication - Abstract
Sep 02, 2020
Scientific Reports
Publication - Abstract
Jul 19, 2020
Current Topics in Microbiology and Immunology
Publication - Abstract
Jun 11, 2020
Pharmaceuticals
Publication - Abstract
May 08, 2020
Vaccines
Publication - Abstract
Mar 13, 2020
Pharmaceutics
Publication - Abstract
Feb 24, 2020
Pharmaceutical Research
Publication - Abstract
Feb 10, 2020
Drug Delivery and Translational Research
Publication - Abstract
Jan 31, 2020
International Journal of Pharmaceutics: X
Publication - Abstract
Jan 09, 2020
Drug Delivery and Translational Research
Publication - Abstract
Dec 31, 2019
Vaccines
Publication - Abstract
Dec 09, 2019
International Journal of Molecular Sciences
Publication - Abstract
Nov 28, 2019
Journal of Controlled Release
Publication - Abstract
Nov 08, 2019
Pharmaceutics
Publication - Abstract
Sep 01, 2019
Journal of Colloid and Interface Science
Publication - Abstract
Jul 31, 2019
European Journal of Biotechnology and Bioscience
Publication - Abstract
Apr 25, 2019
Polymers
Publication - Abstract
Apr 03, 2019
British Journal of Pharmacy
Publication - Abstract
Feb 27, 2019
Cell Chemical Biology
Brent Stockwell’s lab at Columbia University demonstrated the efficacy of a small molecule encapsulated in a PEG-PLGA nanoparticle for inducing a form of cell death called ferroptosis (discovered by the Stockwell Lab) in diffuse large B cell lymphoma (DLBCL) mouse models...
Publication - Abstract
Dec 05, 2018
Journal of Drug Delivery Science and Technology
Publication - Abstract
Oct 08, 2018
Nature Medicine
Publication - Abstract
Jul 04, 2018
Nature communications
Publication - Abstract
Jun 01, 2018
Biological and Pharmaceutical Bulletin
Publication - Abstract
May 07, 2018
Bioconjugate Chemistry
Publication - Abstract
Apr 05, 2018
Advanced Drug Delivery Reviews
Nanopharmaceuticals aim at translating the unique features of nano-scale materials into therapeutic products and consequently their development relies critically on the progression in manufacturing technology to allow scalable processes complying w...
Publication - Abstract
Feb 27, 2018
Langmuir
Controlling the size and narrow size distribution of polymer-based nanocarriers for targeted drug delivery is an important parameter that significantly influences their colloidal stability, biodistribution, and targeting ability. Herein, we report ...
Publication - Abstract
Feb 12, 2018
Journal of Nanobiotechnology
The process of optimization and fabrication of nanoparticle synthesis for preclinical studies can be challenging and time consuming. Traditional small scale laboratory synthesis techniques suffer from batch to batch variability. Additionally, the p...
Publication - Summary
Nov 24, 2017
International Journal of Pharmaceutics
Polymeric nanoparticles are efficient drug delivery vehicles that can deliver a wide range of bioactive agents. Specifically, poly(lactic-co-glycolic acid) copolymer (PLGA) based nanoparticles are biocompatible and biodegradable and approved by the...
Publication - Abstract
Jul 10, 2017
Nature Communications
The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle for tissue repair in central nervous system (CNS). Here we report that injection of imidazole-poly (organophosphazenes) (I-5), a hydrogel with thermosens...
Publication - Summary
May 11, 2017
Biomaterials
Metastatic and multidrug resistant (MDR) tumors are generally very challenging to treat; and while in many cancers early detection can increase the survival rate significantly, the mortality rates of advanced and metastasized cancers are still quit...
Publication - Abstract
Apr 24, 2017
Bioconjugate Chemistry
Polymer conjugation is an attractive approach for delivering insoluble and highly toxic drugs to tumors. However, most reports in the literature only disclose the optimal composition without emphasizing rational design or composition optimization t...
Publication - Abstract
Nov 21, 2016
The AAPS Journal
Cytotoxic chemotherapeutic agents are used as the standard therapy for a range of significant cancers, but many of these drugs suffer from poor water solubility and low selectivity, limiting their clinical efficacy. To overcome these shortcomings, ...
Publication - Abstract
Nov 06, 2016
Langmuir
We compare the microfluidic manufacturing of polycaprolactone-block-poly(ethylene oxide) (PCL-b-PEO) nanoparticles (NPs) in a single-phase staggered herringbone (SHB) mixer and in a two-phase gas–liquid segmented mixer.
Publication - Abstract
Aug 05, 2016
Journal of Drug Targeting
Microfluidic devices are mircoscale fluidic circuits used to manipulate liquids at the nanoliter scale. The ability to control the mixing of fluids and the continuous nature of the process make it apt for solvent/antisolvent precipitation of drug-d...
Publication - Summary
Jan 19, 2016
Proceedings of the National Academy of Sciences
Liver cancer is a deadly disease with limited intervention options. Tumour removal surgery and liver transplantation are extremely complicated and not always possible. Several small molecule drugs aimed to treat hepatocellular carcinoma (HCC) have ...
Publication - Summary
Jun 03, 2015
Biomaterials
Many chemotherapeutic anticancer agents target vital components of cell division and inhibit survival and growth of cancer cells. Anti-tubulin agents for example, target the microtubule complex formed during mitosis and result in cell apoptosis. Read More
Publication - Summary
Aug 25, 2014
International Journal of Pharmaceutics
Metastatic castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer with poor prognosis and very few treatment options. Fractures and bone pain due to loss of bone density caused by bone metastasis is highly prevalent, re...
Application Note
Dec 22, 2018
Application Note
Mar 02, 2017
Application Note
Mar 01, 2017
Application Note
Mar 01, 2017
Video
Aug 04, 2017
2nd Annual Nanomedicine Symposium | Ocular Delivery of mRNA - Patrick Baumhof, CureVac AG
Video
Aug 04, 2017
Dr. Shyam Garg, Formulation Scientist II, Precision NanoSystems Inc. - 2nd Annual Nanomedicines Symposium
Video
Aug 10, 2016
NanoAssemblr® Blaze™ Tech Talk during the 2016 PNI Nanomedicines Symposium
Video
Aug 10, 2016
NanoAssemblr® Benchtop Tech Talk from 2016 Nanomedicine Symposium
Video
Jul 26, 2016
Targeted mRNA delivery to the Liver for Intracellular Enzyme Replacement Therapy | Pierrot Harvie, PhaseRX
Video
Sep 14, 2016
2016 Nanomedicines: Materials, Manufacturing & Therapeutic Applications Symposium, July 16th in Seattle, WA
Introductory talk: James Taylor, CEO, Precision NanoSystems (PNI) - Nanomedicines: Materials, Manuf...
Webinar
Nov 08, 2017
Discover how nanoparticles can deliver vaccines and elicit immune responses and see some of the latest research on mRNA vaccines and immuno-oncology therapeutics. Share this video with others who are interested in the latest in vaccine research.
Webinar
Aug 04, 2017
Webinar
Jun 29, 2017
Dr. Shyam Garg, Formulation Scientist II at Precision NanoSystems Inc.
Webinar
Jun 21, 2016
Microfluidic-mediated self-assembly of liposomes and polymer nanoparticles expands the strategies available to the formulation scientist for the encapsulation and delivery of hydrophobic compounds. In this webinar Dr. James Taylor and Dr. Shyam Gar...
Webinar
Jun 17, 2016
Dr. Shyh-Dar Li from the University of British Columbia introduced the design, synthesis and fabrication of a self-assembled polymeric nanoparticle system, and the use of which to deliver insoluble anticancer drugs for therapy of tumors in preclini...