Publication - Abstract
May 17, 2019
Methods in Molecular Biology, vol 1974
I. Hazan-Halevy, D. Rosenblum, S. Ramishetti, and D. Peer
Systemic delivery of RNA interference (RNAi) payloads for manipulation of gene expression in lymphocytes holds a great potential as a novel therapeutic modality for hematological malignancies and autoimmune disorders. However, lymphocytes are among the most difficult cells to tra...
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Publication - Abstract
Apr 08, 2020
Molecular Pharmaceutics
K. Zhou, L.T. Johnson, H. Xiong, S. Barrios, J.T. Minnig, Y. Yan, B. Abram, X. Yu and D.J.Siegwart
In this work, a series of linear-dendritic poly(ethylene glycol) (PEG) lipids (PEG-GnCm) were synthesized through a strategy using sequential aza- and sulfa-Michael addition reactions. The effect of modulating the hydrophobic domain of linear-dendritic PEG lipids was systematical...
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