Publication - Abstract
Dec 21, 2020
Molecular Therapy
A.K. Blakney, P.F. McKay, C.R. Bouton, K. Hu, K. Samnuan and R.J. Shattock
Abstract
Self-amplifying RNA (saRNA) is a cutting-edge platform for both nucleic acid vaccines and therapeutics. saRNA is self-adjuvanting, as it activates types I and III interferon (IFN), which enhances the immunogenicity of RNA vaccines but can also lead to inhibition...
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Publication - Abstract
Mar 13, 2020
Pharmaceutics
E. Chiesa, F. Riva, R. Dorati, A. Greco, S. Ricci, S. Pisani, M. Patrini, T. Modena, B. Conti and I. Genta
In this study, an innovative microfluidics-based method was developed for one-step synthesis of hyaluronic acid (HA)-based nanoparticles (NPs), by exploiting polyelectrolytic interactions between HA and chitosan (CS), in order to improve reliability, reproducibility and possible ...
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