Publication - Abstract
May 17, 2019
Methods in Molecular Biology, vol 1974
I. Hazan-Halevy, D. Rosenblum, S. Ramishetti, and D. Peer
Systemic delivery of RNA interference (RNAi) payloads for manipulation of gene expression in lymphocytes holds a great potential as a novel therapeutic modality for hematological malignancies and autoimmune disorders. However, lymphocytes are among the most difficult cells to tra...
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Publication - Abstract
Aug 05, 2019
Molecular Therapy
E.J. Sayers, S.E. Peel, A. Schantz, R.M. England, M. Beano, S.M. Bates, A.S. Desai, S. Puri, M.B. Ashford and A.T. Jones
Lipid nanoparticles have great potential for delivering nucleic-acid-based therapeutics, but low efficiency limits their broad clinical translation. Differences in transfection capacity between in vitro models used for nanoparticle pre-clinical testing are poorly understood. To a...
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