Combining disruptive technology platforms with unparalleled genomic medicine development expertise, Precision NanoSystems’ Biopharmaceutical Services accelerates the development of lipid nanoparticle (LNP) formulations and drug products.
Partner with Biopharmaceutical Services to design a payload based on your target gene of interest and develop the formulation, processes, analytics and manufacturing protocols for preclinical to clinical drug development. Our team of scientists optimizes the use of limited materials in scaling drug products from discovery to large-scale manufacturing for a broad range of payloads and carriers with the NanoAssemblr® and GenVoy™ technology platforms. Get started with a well-defined project plan and milestones, deliverables, timeline and budget customized to your needs.
Partner with Biopharmaceutical Services on projects that span the entire drug development process, including proof-of-concept studies in early discovery, lead candidate development in scale-up and optimization and technology transfer of manufacturing processes for cGMP production.
Technology Transfer & Manufacturing
Chemistry Manufacturing & Controls (CMC) Support
Developing the right analytical assays for each stage of your project is critical to ensure success in the path from preclinical to clinical drug development. With deep expertise and technical knowledge of genomic medicines, Biopharmaceutical Services develops and applies advanced analytical methodologies to support the characterization of the drug substance, raw materials and/or nanoparticle formulation. Our analytical development team works across the preclinical, clinical, process development, manufacturing and quality teams from selecting lead candidates during formulation development to ensuring specifications of the drug product remain consistent as production is scaled.
Analytical services for both viral and non-viral genomic medicines include drug product identity confirmation, physical characterization, acceptance testing, stability studies, GMP release testing, toxicology testing and raw material testing.
Analytical instrumentation and technologies to assess drug substances and products include particle size analyzers, bioanalyzers, mass spectrometers, liquid chromatographic systems, cryogenic electron microscopes and flow cytometers.
*Available through third-party
mRNA, siRNA, saRNA, Replicon RNA
Publication - Abstract
July 08, 2020
Advanced Drug Delivery Reviews
Publication - Abstract
October 01, 2020
July 15, 2017
September 20, 2021
April 01, 2018