Publication - Abstract
Dec 21, 2017
Gastroenterology
S. Zhang, L.H. Nguyen, K. Zhou, H. Tu, A. Sehgal, I. Nassour, L. Li, P. Gopal, J. Goodman, A.G. Singal, A. Yopp, Y. Zhang, D.J. Siegwart and H. Zhu
Cytokinesis can fail during normal postnatal liver development, leading to polyploid hepatocytes. We investigated whether inhibiting cytokinesis in the liver slows tumor growth without compromising the health of normal hepatocytes. We inhibited cyt...
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Publication - Summary
Dec 19, 2017
Cell Reports
D. An, J.L. Schneller, A. Frassetto, S. Liang, X. Zhu, J.S. Park, M. Theisen, S.J. Hong, J. Zhou J, R. Rajendran, B. Levy, R. Howell, G. Besin, V. Presnyak, S. Sabnis, K.E. Murphy-Benenato, E.S. Kumarasinghe, T. Salerno and P.G.V. Martini PGV
Inborn errors of metabolism (IEMs) can be relatively straight forward to screen for and diagnose; these disorders however, have currently very limited options for treatment. Methylmalonic acidemia (MMA), is an IEM caused by complete or partial defi...
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