Publication - Abstract
Oct 22, 2019
Scientific Reports
H. Elsana, T.O.B. Olusanya, J. Carr-Wilkinson, S. Darby, A. Faheem, and A.A. Elkordy
In gene delivery, non-viral vectors have become the preferred carrier system for DNA delivery. They can overcome major viral issues such as immunogenicity and mutagenicity. Cationic lipid-mediated gene transfer is one of the most commonly used non-viral vectors, which have been s...
Read More
Publication - Abstract
Nov 21, 2016
Nanoscale
W. Viricel, S. Poirier, A. Mbarek, R.M. Derbali, G. Mayer and J. Leblond
A pH-sensitive molecular switch able to change its conformation upon protonation at endosomal pH values is embedded into the structure of cationic lipidoid materials, thus conferring endosomal escape properties. Involvement of the conformational switch in the endosomal escape pro...
Read More