Publication - Abstract
Dec 21, 2020
Molecular Therapy
A.K. Blakney, P.F. McKay, C.R. Bouton, K. Hu, K. Samnuan and R.J. Shattock
Abstract
Self-amplifying RNA (saRNA) is a cutting-edge platform for both nucleic acid vaccines and therapeutics. saRNA is self-adjuvanting, as it activates types I and III interferon (IFN), which enhances the immunogenicity of RNA vaccines but can also lead to inhibition...
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Publication - Abstract
Jan 09, 2020
Drug Delivery and Translational Research
C.B. Roces, D. Christensen and Y. Perrie
In the formulation of nanoparticles, poly(lactic-co-glycolic acid) (PLGA) is commonly employed due to its Food and Drug Administration and European Medicines Agency approval for human use, its ability to encapsulate a variety of moieties, its biocompatibility and biodegradability...
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