Publication - Abstract
Oct 08, 2018
Nature Medicine
L. Jiang, P. Berraondo, D. Jericó, A. Fontanellas et al.
Acute intermittent porphyria (AIP) results from haploinsufficiency of porphobilinogen deaminase (PBGD), the third enzyme in the heme biosynthesis pathway. Patients with AIP have neurovisceral attacks associated with increased hepatic heme demand. Phenobarbital-challenged mice wit...
Read More
Publication - Abstract
Apr 15, 2020
International Journal of Pharmaceutics
J. Riewe, P. Erfle, S. Melzig, A. Kwade, A. Dietzel, and H. Bunjes
Microsystems offer promising possibilities to produce nanoparticles which can be used as carriers for poorly water-soluble active substances. The aim of the present study was to compare the preparation of lipid nanoparticles by precipitation in different microsystems: A segmented...
Read More