April 26, 2016
In this webinar, Professor Dan Peer from Tel Aviv University will talk about the application of microfluidics for the preparation of targeted lipid nanoparticles entrapping siRNAs (RNA-tLNPs) directed towards lymphocytes . Special emphasis will be made on the ability to conjugate different ligands and monoclonal antibodies to the surface of LNPs to endow them with targeting capabilities. Examples will focus on T cells and malignant B cells and describe how RNA-tLNPs can be utilized for therapeutic gene silencing in hematological B cell malignancies and as a tool to study leukocyte biology.