Publication - Abstract
May 13, 2021
Nature Communications
C. Hunt, S.A. Hartford, G. Gong, et al
The paper demonstrates PNI's mRNA-LNP as highly capable of inducing strong levels of upregulation in target genes with activation levels six to nine fold dependent on amount of gRNA packaged. The paper validates the SAM system in mice as a suitable in vivo model encompassing both...
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Publication - Abstract
Apr 12, 2018
Biomaterials Science
Q. Liu, M. Somiya, M. Iijima, K. Tatematsu and S. Kuroda
Viruses are naturally evolved nanocarriers that can evade host immune systems, attach specifically to the surfaces of target cells, enter the cells through endocytosis, escape from endosomes efficiently, and then transfer their genomes to host cells. Hepatitis B virus (HBV) is a ...
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