The Next Generation Cancer Vaccine Summit will take place at Wyndham Boston Beacon Hill in Boston August 16-18, 2022. Industry leaders will exchange ideas on adjuvant mechanisms, personalized vs off-the-shelf therapies and how best to overcome delivery challenges.
Chat with Precision NanoSystems to learn how to identify, optimize, and scale-up potent LNP compositions using microfluidic platform technologies to rapidly develop cancer vaccines.
August 17, 2022 | 12:15 pm ET
Dr. Jason Coleman will explore how to accelerate development and manufacturing of novel lipid nanoparticle(LNP)-based therapeutics through scalable microfluidic technologies, off-the-shelf reagents, and a novel lipid library.
Given the complexities and challenges for developing genomic cancer vaccines, it is critical to have a scalable and robust manufacturing platform for the development of non-viral delivery methods.
This talk will share insights into a scalable manufacturing platform for RNA-LNPs and the use of this technology for the development of a high-potency self-amplifying (saRNA) LNP vaccine. We will also highlight key considerations for the development of a LNP vaccine drug product.
RNA can be designed to silence, express, and edit specific genes providing a flexible and powerful approach to treating diseases. While the development of RNA vaccines for COVID-19 is an extraordinary achievement, it has revealed that rapid development and scaling up – as well as access to necessary technologies – are required to keep up with emerging variants and to help usher in the new era RNA medicines in other therapeutic areas of unmet medical need.
We are cited in over 500 publications, including the recently published articles focused on cancer vaccines:
Changing the Status Quo of Vaccine Production
Accelerating the Development and Scale-Up of mRNA Vaccines
NanoMedU: Learn More About Lipid Nanoparticle Vaccines
For 10 years, Precision NanoSystems has been lowering barriers to working successfully with RNA drug delivery technologies and furthering this goal, we're proud to provide NanoMedU: a focused classroom and hands-on learning program.
The NxGen mixer enables the reproducible scale-up of mRNA-LNP and other complex nanomedicine formulations
Test batches of up to 20 L/h produced with a single NxGen mixer
Particle characteristics (size and PDI) are consistent
Biological activity maintained