Liquids in Dishes in a Lab
概览

多种活性药物成分 (API) 可以包括到纳米颗粒内,用于不同的应用领域。此类 API 被称为纳米颗粒载体内的负载药物。这些负载药物包括传统小分子药物、蛋白质、多肽和核酸,也可以是它们的组合。多种活性药物成分 (API) 已经可以利用NanoAssemblr®技术包封在多种不同的纳米颗粒载体中,并已见诸 文献报道。

Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
LNP
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  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
Liposomes
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  • Phospholipids
  • Cholesterol
  • PEG-Lipids
Polymer
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  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
Emulsions
Emulsion
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  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
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  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors
Exosomes
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  • Natural cell-derived lipids and proteins
  • Additional synthetic lipids and biomolecules
颗粒类型
活性成分
核酸
多肽和蛋白质
小分子物质
造影剂
载体材料
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  • 可电离脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
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  • 磷脂
  • 胆固醇
  • PEG 脂质
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  • 聚乳酸(如PLGA)
  • 嵌段共聚物(如PEG-b-PLGA)
  • 多糖(如壳聚糖、纤维素)
乳剂
Emulsion
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  • 三油酸甘油酯/POPC
  • 油脂/表面活性剂
有机/无机纳米颗粒
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  • 脂质
  • 贵金属纳米颗粒
  • 稀土金属
  • III-V 族半导体


主要应用领域:造影剂和治疗诊断技术

 

造影类型制剂相关资源
MRI 造影和 RNA 治疗siRNA 脂质纳米颗粒和 Gd 螯合脂质出版物
包封的无机纳米颗粒脂质纳米颗粒和黄金纳米颗粒出版物

 


相关出版物

Publication - Abstract

July 01, 2020

Journal of Controlled Release

Delivery of Self-amplifying mRNA Vaccines by Cationic Lipid Nanoparticles: The Impact of Cationic Lipid Select...

G. Lou, G. Anderluzzi, S.T. Schmidt, S. Woods, S. Gallorini, M. Brazzoli, F. Giusti, I. F...

Read More 阅读更多

Publication - Abstract

May 08, 2020

Vaccines

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

G. Anderluzzi, G. Lou, S. Gallorini, M. Brazzoli, R. Johnson, D.T. O'Hagan, B.C. Baudner a...

Read More 阅读更多

Publication - Abstract

April 02, 2020

Journal of Controlled Release

Design of a Novel Vaccine Nanotechnology-based Delivery System Comprising CpGODN-protein Conjugate Anchored to...

D. Chatzikleanthous, S.T. Schmidt, G. Buffi, I. Paciello, R. Cunliffe, F. Carboni, M.R. Ro...

Read More 阅读更多
Resource Center 资源中心

相关资源

Poster

September 01, 2022

Scale Up Genome Editing of CAR T Cells using Lipid Nanoparticles

Read More 阅读更多 PDF

Application Note

March 15, 2022

Genome Editing of Human Primary T Cells with Lipid Nanoparticles

Read More 阅读更多 PDF

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

Read More 阅读更多 PDF
Resource Center 资源中心

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