The NanoAssemblr™ Benchtop
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Controlled and tuned nanomedicine design
The NanoAssemblr Benchtop is a formulation system that gives researchers reproducibility and ease-of-use for iterating on nanoparticle design and therapeutic delivery experiments. Proprietary microfluidics technology enables controlled, bottom-up, molecular self-assembly of nanoparticles through millisecond mixing of components at nanolitre scale. The NanoAssemblr Benchtop is capable of formulating 1 to 20 mL per batch, which is ideal for low-cost formulation and process development. The quick and precise manufacture of nano-medicines allows for 30+ formulations in a day. Users can control size by process and composition – even tweak process parameters such as mixing ratios, flow rate and lipid composition in order to fine tune size.
The Benchtop instrument harnesses Precision NanoSystems’ microfluidic mixing technology to simplify and control the formulation of nanoparticles. The system allows the encapsulation of constructs using novel excipient design that are difficult or not possible using alternative methods. From nucleic acids to hydrophobic drugs, the Benchtop enables tuning for the optimization of encapsulation efficiency and payload release and activity, whether it be in liposome, lipid nanoparticle or polymeric nanoparticle approaches.