Liquids in Dishes in a Lab

A variety of active pharmaceutical ingredients (APIs) can be packaged into nanoparticles for different applications. The API is referred to as the payload within the nanoparticle carrier.  These payloads include traditional small molecule drugs, proteins, peptides, and nucleic acids or combinations thereof.  Numerous APIs have been encapsulated in a variety of different nanoparticle carriers using NanoAssemblr® technology and reported in the literature. Explore these pages to learn more about the function and formulation of different payloads.

Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors
  • 可电离脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 聚乳酸(如PLGA)
  • 嵌段共聚物(如PEG-b-PLGA)
  • 多糖(如壳聚糖、纤维素)
  • 三油酸甘油酯/POPC
  • 油脂/表面活性剂
  • 脂质
  • 贵金属纳米颗粒
  • 稀土金属
  • III-V 族半导体

Featured Application: Imaging Contrast Agents and Theranostics


Contrast TypeFormulationRelated Resources
MRI contrast with RNA therapeuticsiRNA-LNP with Gd-chelating lipidPublications
Encapsulated inorganic nanoparticle LNP with Gold NanoparticlesPublications


Related Publications

Publication - Abstract

July 01, 2020

Journal of Controlled Release

Delivery of Self-amplifying mRNA Vaccines by Cationic Lipid Nanoparticles: The Impact of Cationic Lipid Selection

G. Lou, G. Anderluzzi, S.T. Schmidt, S. Woods, S. Gallorini, M. Brazzoli, F. Giusti, I. Ferlenghi, R. Johnson, C.W. Rob...

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Publication - Abstract

May 08, 2020


Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

G. Anderluzzi, G. Lou, S. Gallorini, M. Brazzoli, R. Johnson, D.T. O'Hagan, B.C. Baudner and Y. Perrie

Read More 阅读更多

Publication - Abstract

April 02, 2020

Journal of Controlled Release

Design of a Novel Vaccine Nanotechnology-based Delivery System Comprising CpGODN-protein Conjugate Anchored to Liposomes

D. Chatzikleanthous, S.T. Schmidt, G. Buffi, I. Paciello, R. Cunliffe, F. Carboni, M.R. Romano, D.T. O'Hagan, U. D'Oro, ...

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Resource Center 资源中心

Related Resources

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

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July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

Read More 阅读更多 PDF

Application Note

January 02, 2018

Seamless scale up of siRNA LNP formulations using the NanoAssemblr® platform

Read More 阅读更多 PDF
Resource Center 资源中心

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