The proprietary NxGen microfluidic mixer enables the reproducible scale-up of mRNA lipid nanoparticles by preserving the critical conditions at the point of formulation.
The scalability and reproducibility of PNI’s NanoAssemblr platform allowed us to move into GMP manufacturing with greater control over the process and increased precision in the final product compared to our previous macromixing process, allowing acceleration of our time to commercialization.
Chief Scientific Officer
Our government is bringing back the vaccine manufacturing capacity that Canadians expect and need. These investments will help to ensure that Canada has modern, flexible vaccine manufacturing capabilities now and in the future. With the investments announced today, our government is helping Canadian...Read More
Minister of Innovation, Science and Industry
Government of Canada
The NanoAssemblr Blaze from Precision NanoSystems is very good for the rapid scale-up of nanoparticle-based formulations. We were able to seamlessly transition our formulation developed on the NanoAssemblr Benchtop to the Blaze instrument and make large scale batches on the Blaze. The Blaze instrume...Read More
Senior Director, Head of Non-Viral Delivery
We look forward to working with Precision NanoSystems to support research efforts around the discovery of novel sLNPs that we believe have the potential to significantly improve and broaden biodistribution. sLNPs represent an exciting and innovative approach in Alnylam’s advancement of proprietary L...Read More
Chief Scientific Officer
We are excited about this promising collaboration and hope that it will propel our work forward as the ncRNA Core Facility focuses on the non-coding RNA portions of the genome for [the] discovery of novel biomarkers and targets for therapeutics from human disease tissue and clinical trial specimens.
Director of Initiative for RNA
Harvard Medical School
As an Evonik affiliate specialized in liposomal drug delivery systems, we are pleased to offer our clients access to the NanoAssemblr GMP System, which will aid in the translation of drug candidates to clinical testing and ideally to commercial use.
Evonik Vancouver Laboratories
Of particular note is LM03PE which had IgG levels of almost 108 ng/mL. We've never seen antibody levels this high.
Comments on PNI's proprietary RNA-LNP formulations eliciting a strong immune response in an influenza challenge study
Marie Skłodowska-Curie Research Fellow
Imperial College London
The ease, reproducibility, and the robustness of PNI’s products is amazing compared to what we previously had used, and that’s been a real enabling factor for Guide as we’ve continued to grow over the last year and a half.
Chief Technology Officer
Our team has been dedicated to developing safe and effective vaccines to fight against the COVID-19 pandemic. Since RNA vaccines are a disruptive technology as they do not require cell culture, utilize synthetic delivery and have a smaller manufacturing footprint, our partnership with PNI to advanc...Read More
Co-founder, Chairman and CEO