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Discovery

The physiological, cellular, and/or genetic basis of a disease is studied to identify potential therapeutic targets. 

 

Development

Once a potential target has been identified, researchers will then screen thousands of APIs, excipients and/or formulations for potential candidates that acts on this target.

 

After early testing, however, only a small number of compounds look promising and call for further study. 

 

We are in the age of cell therapy and gene therapy with bioprocessing being a key elements. Being able to affect disease at the molecular level is the key, and nanomedicine is a fundamental technology for ushering in the next wave of genetic and molecularly targeted therapeutics. 


The NanoAssemblr™ product suite and Formulation Solutions

nanoassemblr-spark

 

The NanoAssemblr Spark™ produces microlitre volumes of nanomedicines for discovery research

benchtop

 

The NanoAssemblr Benchtop manufactures 1 – 15 mL of nanomedicine per run for nanomedicine development programs

formulation-solutions

 

 

To rapidly reach the formulation proof of concept stage PNI offers highly qualified scientist with extensive formulation development experience through our Formulation Solutions Team.                                                                                                                                           

 

At every step, our multidisciplinary experts will partner with you to build affirm scientific foundation for the work ahead.


Get Started

To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

Get in Touch

Resource Center

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

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Application Note

July 01, 2018

Seamless scale up of liposomal verteporfin formulations using the NanoAssemblr™ Platform

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Publication - Abstract

April 26, 2018

Small Methods

State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Evers, M. J. W., Kulkarni, J. A., van der Meel, R., Cullis, P. R., Vader, P., & Schiffelers, R. M.

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Publication - Abstract

February 27, 2018

Cell Reports

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

J. Finn, A. Smith, M. Patel, L. Shaw, M. Youniss, J. Heteren, T. Dirstine, C. Ciullo, R. Lescarbeau, J. Seitzer, R. Shah...

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Publication - Abstract

July 04, 2018

Nature communications

Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

M Yu, L Xu, F Tian, Q Su, N Zheng, Y Yang

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Publication - Abstract

June 15, 2018

Molecular therapy

Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis

E Robinson, KD MacDonald, K Slaughter, M McKinney

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Resource Center