Liquids in Dishes in a Lab
Overview

A variety of active pharmaceutical ingredients (APIs) can be packaged into nanoparticles for different applications. The API is referred to as the payload within the nanoparticle carrier.  These payloads include traditional small molecule drugs, proteins, peptides, and nucleic acids or combinations thereof.  Numerous APIs have been encapsulated in a variety of different nanoparticle carriers using NanoAssemblr® technology and reported in the literature. Explore these pages to learn more about the function and formulation of different payloads.

Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
Emulsions
  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors
颗粒类型
活性成分
核酸
多肽和蛋白质
小分子物质
造影剂
载体材料
  • 可电离脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 聚乳酸(如PLGA)
  • 嵌段共聚物(如PEG-b-PLGA)
  • 多糖(如壳聚糖、纤维素)
乳剂
  • 三油酸甘油酯/POPC
  • 油脂/表面活性剂
有机/无机纳米颗粒
  • 脂质
  • 贵金属纳米颗粒
  • 稀土金属
  • III-V 族半导体


Featured Application: Imaging Contrast Agents and Theranostics

 

Contrast TypeFormulationRelated Resources
MRI contrast with RNA therapeuticsiRNA-LNP with Gd-chelating lipidPublications
Encapsulated inorganic nanoparticle LNP with Gold NanoparticlesPublications

 


Related Publications

Publication - Summary

May 18, 2019

Annals of Hematology

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo

N. Jyotsana, A. Sharma, A. Chaturvedi, et al.

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Publication - Summary

May 17, 2019

Science Immunology

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

N. Kose, J.M. Fox, G. Sapparapu, et al.

Read More 阅读更多

Publication - Summary

April 04, 2019

The Journal of Neuroscience

PTCD1 is required for mitochondrial oxidative-phosphorylation: possible genetic association with Alzheimer's disease

D. Fleck, L. Phu, E. Verschueren, T. Hinkle, M. Reichelt, T. Bhangale, B. Haley, Y. Wang, R. Graham, D.S. Kirkpatrick, M...

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Resource Center 资源中心

Related Resources

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

Read More 阅读更多 PDF

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

Read More 阅读更多 PDF

Application Note

January 02, 2018

Seamless scale up of siRNA LNP formulations using the NanoAssemblr® platform

Read More 阅读更多 PDF
Resource Center 资源中心

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