Liquids in Dishes in a Lab
Overview

A variety of active pharmaceutical ingredients (APIs) can be packaged into nanoparticles for different applications. The API is referred to as the payload within the nanoparticle carrier.  These payloads include traditional small molecule drugs, proteins, peptides, and nucleic acids or combinations thereof.  Numerous APIs have been encapsulated in a variety of different nanoparticle carriers using NanoAssemblr® technology and reported in the literature. Explore these pages to learn more about the function and formulation of different payloads.

Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
Emulsions
  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors


Featured Application: Imaging Contrast Agents and Theranostics

 

Contrast TypeFormulationRelated Resources
MRI contrast with RNA therapeuticsiRNA-LNP with Gd-chelating lipidPublications
Encapsulated inorganic nanoparticle LNP with Gold NanoparticlesPublications

 


Related Publications

Publication - Summary

April 04, 2019

The Journal of Neuroscience

PTCD1 is required for mitochondrial oxidative-phosphorylation: possible genetic association with Alzheimer's disease

D. Fleck, L. Phu, E. Verschueren, T. Hinkle, M. Reichelt, T. Bhangale, B. Haley, Y. Wang, R. Graham, D.S. Kirkpatrick, M...

Read More

Publication - Summary

February 07, 2019

Nano Research

Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast can...

C. Zhang, X. Zhang, W. Zhao, C. Zeng, W. Li, B. Li, X. Luo, J. Li, J. Jiang, B. Deng, D.W. McComb, Y. Dong

Read More

Publication - Summary

September 24, 2018

Nucleic Acid Therapeutics

MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct

R. Jain, JP. Frederick, EY. Huang, KE. Burke, DM. Mauger, EA. Andrianova, SJ. Farlow, S. Siddiqui, J. Pimentel, K. Cheun...

Read More
Resource Center

Related Resources

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

Read More PDF

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

Read More PDF

Application Note

January 02, 2018

Seamless scale up of siRNA LNP formulations using the NanoAssemblr® platform

Read More PDF
Resource Center

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