Scientist Holding Small Formulation
Adaptable Nanoparticle Research and Development
Using NanoAssmemblr® technology, develop a broad range of nanoparticle formulations, varying in size, payload and excipient characteristics. Find new designs for difficult-to-deliver drugs and hard-to-treat targets.


Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
Emulsions
  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors
颗粒类型
活性成分
核酸
多肽和蛋白质
小分子物质
造影剂
载体材料
  • 可电离脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
  • 聚乳酸(如PLGA)
  • 嵌段共聚物(如PEG-b-PLGA)
  • 多糖(如壳聚糖、纤维素)
乳剂
  • 三油酸甘油酯/POPC
  • 油脂/表面活性剂
有机/无机纳米颗粒
  • 脂质
  • 贵金属纳米颗粒
  • 稀土金属
  • III-V 族半导体


Precision NanoSystems technology has enabled the development of a broad range of nanoparticle formulations, varying in size (20nm to 200nm), payload (e.g. nucleic acids, hydrophobic drugs) and excipient characteristics (e.g. charge and pH tuning). With the ability to iterate and tune particle characteristics faster than before, researchers are finding new designs and opening up possibilities for targets and drugs that previously would have been difficult or taken too long to develop.

In addition to the above, other particle types have also been developed on the NanoAssemblr® platform.

Particle TypeCompositionRelated Resources
NiosomesNon-ionic surfactant-based VesicleView Paper
Nano-lipomerHybrid particles made of lipids and polymers View Paper
Dendrimer NanoparticleModular biodegradable dendrimer carrying miRNAView Paper

Related Publications

Publication - Summary

May 18, 2019

Annals of Hematology

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo

N. Jyotsana, A. Sharma, A. Chaturvedi, et al.

Read More 阅读更多

Publication - Summary

May 17, 2019

Science Immunology

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

N. Kose, J.M. Fox, G. Sapparapu, et al.

Read More 阅读更多

Publication - Summary

April 04, 2019

The Journal of Neuroscience

PTCD1 is required for mitochondrial oxidative-phosphorylation: possible genetic association with Alzheimer's disease

D. Fleck, L. Phu, E. Verschueren, T. Hinkle, M. Reichelt, T. Bhangale, B. Haley, Y. Wang, R. Graham, D.S. Kirkpatrick, M...

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Resource Center 资源中心

Related Resources

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

Read More 阅读更多 PDF

Poster

July 01, 2018

Robust low-volume production of nanoparticles for genetic manipulation of cells

Read More 阅读更多 PDF

Application Note

January 02, 2018

Seamless scale up of siRNA LNP formulations using the NanoAssemblr® platform

Read More 阅读更多 PDF
Resource Center 资源中心

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